BPT1/YLL015W Summary Help

Standard Name BPT1 1
Systematic Name YLL015W
Feature Type ORF, Verified
Description ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p (1, 2, 3)
Name Description Bile Pigment Transporter 1
Chromosomal Location
ChrXII:116432 to 121111 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All BPT1 GO evidence and references
  View Computational GO annotations for BPT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Large-scale survey
null
Resources
44 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • PCA: 8
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Negative Genetic: 18
  • Phenotypic Enhancement: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,559
Molecular Weight (Da) 176,872
Isoelectric Point (pI) 7.63
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:116432 to 121111 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4680 116432..121111 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003938
References cited on this page View Complete Literature Guide for BPT1
1) Petrovic S, et al.  (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71
2) Bauer BE, et al.  (1999) Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim Biophys Acta 1461(2):217-36
3) Klein M, et al.  (2002) The ATP-binding cassette (ABC) transporter Bpt1p mediates vacuolar sequestration of glutathione conjugates in yeast. FEBS Lett 520(1-3):63-7