DRS1/YLL008W Summary Help

DRS1 BASIC INFORMATION

Standard Name DRS1
Systematic Name YLL008W
Feature Type ORF, Verified
Description Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles (1, 2, 3)
Name Description Deficiency of Ribosomal Subunits 4
GO Annotations All DRS1 GO evidence and references
    View Computational GO annotations for DRS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All DRS1 Phenotype details and references
Classical genetics
conditional
dominant negative
null
Large-scale survey
null
Interactions DRS1 All interactions details and references
94 total interaction(s) for 69 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 70
  • Biochemical Activity: 18
  • Two-hybrid: 1
Genetic Interactions
  • Phenotypic Enhancement: 1
  • Synthetic Lethality: 4
Sequence Information
ChrXII:131728 to 133986 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2259 131728..133986 1996-07-31 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003931

DRS1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for DRS1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DRS1]

1) Ripmaster TL, et al.  (1993) DRS1 to DRS7, novel genes required for ribosome assembly and function in Saccharomyces cerevisiae. Mol Cell Biol 13(12):7901-12
2) Adams CC, et al.  (2002) Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits. RNA 8(2):150-65
3) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27
4) Ripmaster TL, et al.  (1992) A putative ATP-dependent RNA helicase involved in Saccharomyces cerevisiae ribosome assembly. Proc Natl Acad Sci U S A 89(23):11131-5