HMS2/YJR147W Summary Help

Standard Name HMS2 1
Systematic Name YJR147W
Feature Type ORF, Verified
Description Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant; HMS2 has a paralog, SKN7, that arose from the whole genome duplication (1, 2)
Name Description High-copy Mep Suppressor 1
Chromosomal Location
ChrX:704196 to 705272 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HMS2 GO evidence and references
  View Computational GO annotations for HMS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 22 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
46 total interaction(s) for 40 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Two-hybrid: 34

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 5
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 358
Molecular Weight (Da) 41,192
Isoelectric Point (pI) 9.71
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:704196 to 705272 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1077 704196..705272 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003908
References cited on this page View Complete Literature Guide for HMS2
1) Lorenz MC and Heitman J  (1998) Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics 150(4):1443-57
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61