MCM22/YJR135C Summary Help

MCM22 BASIC INFORMATION

Standard Name MCM22
Systematic Name YJR135C
Feature Type ORF, Verified
Description Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner (1, 2)
Name Description MiniChromosome Maintenance 3
GO Annotations All MCM22 GO evidence and references
    View Computational GO annotations for MCM22
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All MCM22 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions MCM22 All interactions details and references
109 total interaction(s) for 61 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-Western: 4
  • Two-hybrid: 13
Genetic Interactions
  • Dosage Lethality: 1
  • Phenotypic Enhancement: 17
  • Synthetic Growth Defect: 21
  • Synthetic Lethality: 25
Sequence Information
ChrX:676768 to 676049 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..720 676768..676049 2009-02-18 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003896

MCM22 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for MCM22

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MCM22]

1) Poddar A, et al.  (1999) MCM21 and MCM22, two novel genes of the yeast Saccharomyces cerevisiae are required for chromosome transmission. Mol Microbiol 31(1):349-60
2) Measday V, et al.  (2002) Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore. Genes Dev 16(1):101-13
3) Maine GT, et al.  (1984) Mutants of S. cerevisiae defective in the maintenance of minichromosomes. Genetics 106(3):365-85