NMD5/YJR132W Summary

NMD5 BASIC INFORMATION

Standard Name	NMD5
Systematic Name	YJR132W
Alias	KAP119
Feature Type	ORF, Verified
Description	Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog (1, 2, 3)

GO Annotations	All NMD5 GO evidence and references
	View Computational GO annotations for NMD5
Molecular Function
Manually curated	protein transporter activity (IDA, IMP)
Biological Process
Manually curated	protein import into nucleus (IMP, ISS)
Cellular Component
Manually curated	cytoplasm (IDA) nucleus (IDA)

Interactions	NMD5 All interactions details and references
	77 total interaction(s) for 71 unique genes/features.
Physical Interactions	Affinity Capture-MS: 16 Affinity Capture-RNA: 1 Affinity Capture-Western: 8 Co-localization: 1 Reconstituted Complex: 3 Two-hybrid: 4
Genetic Interactions	Phenotypic Enhancement: 9 Phenotypic Suppression: 35

Sequence Information

ChrX:669512 to 672658 | |

Last Update

Coordinates: 2009-02-18 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3147	669512..672658	2009-02-18	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003893

NMD5 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for NMD5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NMD5]

1)	Albertini M, et al. (1998) A novel nuclear import pathway for the transcription factor TFIIS. J Cell Biol 143(6):1447-55
2)	Ferrigno P, et al. (1998) Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J 17(19):5606-14
3)	Polizotto RS and Cyert MS (2001) Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p. J Cell Biol 154(5):951-60

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