BUD4/YJR092W Summary

BUD4 BASIC INFORMATION

Standard Name	BUD4 1
Systematic Name	YJR092W
Feature Type	ORF, Verified
Description	Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate (1, 2)
Name Description	BUD site selection

GO Annotations	All BUD4 GO evidence and references
	View Computational GO annotations for BUD4
Molecular Function
Manually curated	GTP binding (ISS)
Biological Process
Manually curated	axial cellular bud site selection (TAS) cellular bud site selection (TAS)
Cellular Component
Manually curated	cellular bud neck contractile ring (TAS)

Mutant Phenotype	All BUD4 Phenotype details and references
Classical genetics
null	axial budding pattern: decreased bipolar budding pattern: increased
reduction of function	axial budding pattern: decreased bipolar budding pattern: increased
unspecified	axial budding pattern: decreased liquid culture appearance: abnormal
Large-scale survey
null	bud morphology: abnormal viable

Interactions	BUD4 All interactions details and references
	33 total interaction(s) for 30 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Affinity Capture-Western: 3 Biochemical Activity: 11 Two-hybrid: 2
Genetic Interactions	Dosage Lethality: 1 Phenotypic Enhancement: 2 Phenotypic Suppression: 1 Synthetic Growth Defect: 3 Synthetic Rescue: 1

Sequence Information

ChrX:598727 to 603070 | |

Last Update

Coordinates: 2009-02-18 | Sequence: 2008-06-04

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..4344	598727..603070	2009-02-18	2008-06-04

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003852

BUD4 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BUD4

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BUD4]

1)	Chant J and Herskowitz I (1991) Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell 65(7):1203-12
2)	Sanders SL and Herskowitz I (1996) The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner. J Cell Biol 134(2):413-27

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