GRR1/YJR090C Summary 
| Standard Name | GRR1 (see Nomenclature conflict Note) |
|---|---|
| Systematic Name | YJR090C |
| Alias | CAT80 , COT2 1 , SSU2 , SDC1 |
| Feature Type | ORF, Verified |
| Description | F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification (1, 2, 3, 4, 5, 6, 7, 8) |
| Name Description | Glucose Repression-Resistant 9 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
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| Genetic position: 60 cM |
Gene Ontology Annotations All GRR1 GO evidence and references
| View Computational GO annotations for GRR1 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| High-throughput | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All GRR1 Phenotype evidence and references
interactions All GRR1 Interaction evidence and references
| 149 total interaction(s) for 75 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All GRR1 Protein evidence and references
| Localization | |
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| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Genetic position: 60 cM | |||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000003850 |
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NOMENCLATURE CONFLICT NOTE
| Name | Relevance | Description |
|---|---|---|
| SDC1 | Nomenclature conflict | SDC1 has been used in the literature to refer to both SDC1/YDR469W and GRR1/YJR090C. |
References cited on this page View Complete Literature Guide for GRR1
| 1) | Conklin DS, et al. (1993) The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae. Mol Cell Biol 13(4):2041-9 |
| 2) | Kim YJ, et al. (1994) Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol 127(5):1381-94 |
| 3) | Erickson JR and Johnston M (1994) Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136(4):1271-8 |
| 4) | Vallier LG, et al. (1994) Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136(4):1279-85 |
| 5) | Li FN and Johnston M (1997) Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J 16(18):5629-38 |
| 6) | Barral Y, et al. (1995) G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev 9(4):399-409 |
| 7) | Avram D and Bakalinsky AT (1996) Multicopy FZF1 (SUL1) suppresses the sulfite sensitivity but not the glucose derepression or aberrant cell morphology of a grr1 mutant of Saccharomyces cerevisiae. Genetics 144(2):511-21 |
| 8) | Flick JS and Johnston M (1991) GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol Cell Biol 11(10):5101-12 |
| 9) | Bailey RB and Woodword A (1984) Isolation and characterization of a pleiotropic glucose repression resistant mutant of Saccharomyces cerevisiae. Mol Gen Genet 193(3):507-12 |
