Standard Name	GPI14 1
Systematic Name	YJR013W
Alias	PMH1 2
Feature Type	ORF, Verified
Description	Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M (3, 4)
Name Description	GlycosylPhosphatidylInositol anchor biosynthesis 1

Chromosomal Location	ChrX:460382 to 461593 | ORF Map | GBrowse

	View Computational GO annotations for GPI14
Molecular Function
Manually curated	mannosyltransferase activity (ISS)
Biological Process
Manually curated	fungal-type cell wall organization (IMP) GPI anchor biosynthetic process (IMP, ISS)
Cellular Component
Manually curated	endoplasmic reticulum membrane (ISS)
High-throughput	integral to membrane (ISM)

Classical genetics
null	resistance to caffeine: decreased
Large-scale survey
null	haploinsufficient inviable resistance to mefloquine: decreased
reduction of function	competitive fitness: increased resistance to methyl methanesulfonate: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	9 total interaction(s) for 8 unique genes/features.
Physical Interactions	Two-hybrid: 2
Genetic Interactions	Negative Genetic: 3 Positive Genetic: 1 Synthetic Growth Defect: 1 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:460382 to 461593 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2004-02-12
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1212 460382..461593 2011-02-03 2004-02-12
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003774