POL31/YJR006W Summary Help

POL31 BASIC INFORMATION

Standard Name POL31 1
Systematic Name YJR006W
Alias HUS2 , SDP5 2 , HYS2 3
Feature Type ORF, Verified
Description DNA polymerase III (delta) subunit, essential for cell viability; involved in DNA replication and DNA repair (1, 4, 5)
Name Description POLymerase 1
GO Annotations All POL31 GO evidence and references
    View Computational GO annotations for POL31
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All POL31 Phenotype details and references
Large-scale survey
conditional
null
Interactions POL31 All interactions details and references
60 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-Western: 5
  • Co-purification: 1
  • Reconstituted Complex: 5
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 3
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 16
  • Phenotypic Suppression: 3
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 7
  • Synthetic Rescue: 6

Sequence Information
ChrX:449194 to 450657 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1464 449194..450657 2009-02-18 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003766

POL31 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for POL31]

1) Gerik KJ, et al.  (1998) Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta. J Biol Chem 273(31):19747-55
2) Giot L, et al.  (1995) Suppressors of thermosensitive mutations in the DNA polymerase delta gene of Saccharomyces cerevisiae. Mol Gen Genet 246(2):212-22
3) Sugimoto K, et al.  (1995) HYS2, an essential gene required for DNA replication in Saccharomyces cerevisiae. Nucleic Acids Res 23(17):3493-500
4) Giot L, et al.  (1997) Involvement of the yeast DNA polymerase delta in DNA repair in vivo. Genetics 146(4):1239-51
5) Hashimoto K, et al.  (1998) The second subunit of DNA polymerase III (delta) is encoded by the HYS2 gene in Saccharomyces cerevisiae. Nucleic Acids Res 26(2):477-85