CBP1/YJL209W Summary Help

Standard Name CBP1 1
Systematic Name YJL209W
Feature Type ORF, Verified
Description Mitochondrial protein, regulator of COB mRNA stability and translation; interacts with the 5'-untranslated region of the COB mRNA; found in a complex at the inner membrane along with Pet309p; localizes to mitochondrial foci upon DNA replication stress (2, 3)
Name Description Cytochrome B mRNA Processing 1
Chromosomal Location
ChrX:38005 to 39969 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CBP1 GO evidence and references
  View Computational GO annotations for CBP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
conditional
reduction of function
Large-scale survey
null
Resources
10 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 4

Genetic Interactions
  • Dosage Growth Defect: 1
  • Phenotypic Suppression: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 654
Molecular Weight (Da) 76,171
Isoelectric Point (pI) 10.36
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:38005 to 39969 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1965 38005..39969 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003745
References cited on this page View Complete Literature Guide for CBP1
1) Dieckmann CL, et al.  (1982) Identification and cloning of a yeast nuclear gene (CBP1) involved in expression of mitochondrial cytochrome b. Proc Natl Acad Sci U S A 79(6):1805-9
2) Krause K, et al.  (2004) The mitochondrial message-specific mRNA protectors Cbp1 and Pet309 are associated in a high-molecular weight complex. Mol Biol Cell 15(6):2674-83
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76