HSP150/YJL159W Summary Help

HSP150 BASIC INFORMATION

Standard Name HSP150
Systematic Name YJL159W
Alias CCW7 1 , ORE1 , PIR2
Feature Type ORF, Verified
Description O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation (2, 3, 4, 5, 6, 7, 8)
Name Description Heat Shock Protein 6
GO Annotations All HSP150 GO evidence and references
    View Computational GO annotations for HSP150
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All HSP150 Phenotype details and references
Large-scale survey
null
Interactions HSP150 All interactions details and references
13 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
Genetic Interactions
  • Dosage Rescue: 3
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1
Sequence Information
ChrX:120445 to 121686 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-10-04 | Sequence: 2006-10-04
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1242 120445..121686 2006-10-04 2006-10-04
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003695

HSP150 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for HSP150

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HSP150]

1) Mrsa V, et al.  (1997) Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. Yeast 13(12):1145-54
2) Mrsa V and Tanner W  (1999) Role of NaOH-extractable cell wall proteins Ccw5p, Ccw6p, Ccw7p and Ccw8p (members of the Pir protein family) in stability of the Saccharomyces cerevisiae cell wall. Yeast 15(10A):813-20
3) Ezaki B, et al.  (1998) Protective roles of two aluminum (Al)-induced genes, HSP150 and SED1 of Saccharomyces cerevisiae, in Al and oxidative stresses. FEMS Microbiol Lett 159(1):99-105
4) Russo P, et al.  (1993) Dual regulation by heat and nutrient stress of the yeast HSP150 gene encoding a secretory glycoprotein. Mol Gen Genet 239(1-2):273-80
5) Kapteyn JC, et al.  (1999) The contribution of the O-glycosylated protein Pir2p/Hsp150 to the construction of the yeast cell wall in wild-type cells and beta 1,6-glucan-deficient mutants. Mol Microbiol 31(6):1835-44
6) Russo P, et al.  (1992) A heat shock gene from Saccharomyces cerevisiae encoding a secretory glycoprotein. Proc Natl Acad Sci U S A 89(9):3671-5
7) Toh-e A, et al.  (1993) Three yeast genes, PIR1, PIR2 and PIR3, containing internal tandem repeats, are related to each other, and PIR1 and PIR2 are required for tolerance to heat shock. Yeast 9(5):481-94
8) Moukadiri I and Zueco J  (2001) Evidence for the attachment of Hsp150/Pir2 to the cell wall of Saccharomyces cerevisiae through disulfide bridges. FEMS Yeast Res 1(3):241-5