RPA34/YJL148W Summary

RPA34 BASIC INFORMATION

Standard Name	RPA34 1
Systematic Name	YJL148W
Feature Type	ORF, Verified
Description	RNA polymerase I subunit A34.5 (1)
Name Description	RNA Polymerase A
Gene Product Alias	A34.5 2

GO Annotations	All RPA34 GO evidence and references
	View Computational GO annotations for RPA34
Molecular Function
Manually curated	DNA-directed RNA polymerase activity (TAS)
Biological Process
Manually curated	transcription of nuclear rRNA large RNA polymerase I transcript (IGI)
Cellular Component
Manually curated	DNA-directed RNA polymerase I complex (IDA, IMP) nucleolus (IDA) nucleus (IDA)

Mutant Phenotype	All RPA34 Phenotype details and references
Classical genetics
null	chromosome/plasmid maintenance: abnormal Nop1p distribution: abnormal vegetative growth: decreased viable
Large-scale survey
null	chitin deposition: normal competitive fitness: decreased hyperosmotic stress resistance: decreased resistance to Calcofluor White: normal resistance to 5-fluorouracil: decreased resistance to doxorubicin: decreased sporulation: abnormal viable

Interactions	RPA34 All interactions details and references
	302 total interaction(s) for 210 unique genes/features.
Physical Interactions	Affinity Capture-MS: 43 Affinity Capture-Western: 3 Biochemical Activity: 4 PCA: 7 Reconstituted Complex: 1 Two-hybrid: 7
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 131 Phenotypic Suppression: 63 Synthetic Growth Defect: 11 Synthetic Lethality: 31

Sequence Information

ChrX:140433 to 141134 | |

Last Update

Coordinates: 2009-02-18 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..702	140433..141134	2009-02-18	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003684

RPA34 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RPA34

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RPA34]

1)	Gadal O, et al. (1997) A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine. Mol Cell Biol 17(4):1787-95
2)	Riva M, et al. (1982) Natural variation in yeast RNA polymerase A. Formation of a mosaic RNA polymerase A in a meiotic segregant from an interspecific hybrid. J Biol Chem 257(8):4570-7

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