TRK1/YJL129C Summary Help

Standard Name TRK1 1
Systematic Name YJL129C
Feature Type ORF, Verified
Description Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation; TRK1 has a paralog, TRK2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description TRansport of potassium (K)
Chromosomal Location
ChrX:177306 to 173599 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TRK1 GO evidence and references
  View Computational GO annotations for TRK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
102 total interaction(s) for 55 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • PCA: 2
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 3
  • Dosage Rescue: 9
  • Negative Genetic: 3
  • Phenotypic Enhancement: 12
  • Phenotypic Suppression: 6
  • Synthetic Growth Defect: 26
  • Synthetic Lethality: 7
  • Synthetic Rescue: 26

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,235
Molecular Weight (Da) 141,072
Isoelectric Point (pI) 8.87
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:177306 to 173599 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3708 177306..173599 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003665
References cited on this page View Complete Literature Guide for TRK1
1) Gaber RF, et al.  (1988) TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cerevisiae. Mol Cell Biol 8(7):2848-59
2) Ko CH and Gaber RF  (1991) TRK1 and TRK2 encode structurally related K+ transporters in Saccharomyces cerevisiae. Mol Cell Biol 11(8):4266-73
3) Yenush L, et al.  (2005) pH-Responsive, posttranslational regulation of the Trk1 potassium transporter by the type 1-related Ppz1 phosphatase. Mol Cell Biol 25(19):8683-92
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61