CCT7/YJL111W Summary Help

Standard Name CCT7
Systematic Name YJL111W
Alias TCP7
Feature Type ORF, Verified
Description Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; mutant has increased aneuploidy tolerance (1, 2, 3)
Name Description Chaperonin Containing TCP-1
Chromosomal Location
ChrX:207877 to 209529 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CCT7 GO evidence and references
  View Computational GO annotations for CCT7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Large-scale survey
null
overexpression
Resources
45 total interaction(s) for 35 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 32
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 1
  • Biochemical Activity: 3
  • Co-fractionation: 1
  • Co-purification: 1
  • PCA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Phenotypic Enhancement: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 550
Molecular Weight (Da) 59,735
Isoelectric Point (pI) 5.32
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:207877 to 209529 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1653 207877..209529 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003647
References cited on this page View Complete Literature Guide for CCT7
1) Stoldt V, et al.  (1996) Review: the Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeasts. Yeast 12(6):523-9
2) Kim S, et al.  (1994) Cystosolic chaperonin subunits have a conserved ATPase domain but diverged polypeptide-binding domains. Trends Biochem Sci 19(12):543-8
3) Torres EM, et al.  (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83