Standard Name	CHS6
Systematic Name	YJL099W
Alias	CSD3
Feature Type	ORF, Verified
Description	Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; CHS6 has a paralog, BCH2, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description	CHitin Synthase-related 6

Chromosomal Location	ChrX:239414 to 241654 | ORF Map | GBrowse

	View Computational GO annotations for CHS6
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	fungal-type cell wall chitin biosynthetic process (IMP) Golgi to plasma membrane transport (IGI, IMP)
Cellular Component
Manually curated	exomer complex (IDA) colocalizes_with trans-Golgi network transport vesicle (IDA)
High-throughput	colocalizes_with clathrin-coated vesicle (IDA)

Classical genetics
null	heat sensitivity: increased protein transport: abnormal resistance to Calcofluor White: increased
reduction of function	chitin deposition: decreased osmotic stress resistance: decreased resistance to Calcofluor White: increased
Large-scale survey
null	chitin deposition: decreased competitive fitness: decreased resistance to Calcofluor White: increased resistance to bleomycin: increased resistance to camptothecin: increased resistance to fenpropimorph: increased resistance to fluconazole: increased resistance to methyl methanesulfonate: increased resistance to caffeine: decreased resistance to ciclopirox olamine: decreased resistance to tunicamycin: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	203 total interaction(s) for 112 unique genes/features.
Physical Interactions	Affinity Capture-MS: 10 Affinity Capture-RNA: 2 Affinity Capture-Western: 9 Co-crystal Structure: 1 Co-purification: 3 Reconstituted Complex: 4 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 86 Phenotypic Enhancement: 2 Phenotypic Suppression: 3 Positive Genetic: 1 Synthetic Growth Defect: 23 Synthetic Lethality: 45 Synthetic Rescue: 11
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:239414 to 241654 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2241 239414..241654 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003635