SAP185/YJL098W Summary Help

Standard Name SAP185 1
Systematic Name YJL098W
Feature Type ORF, Verified
Description Protein that forms a complex with the Sit4p protein phosphatase; required for Sit4p function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p; SAP185 has a paralog, SAP190, that arose from the whole genome duplication (1, 2)
Name Description Sit4 Associated Protein 1
Chromosomal Location
ChrX:242082 to 245258 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SAP185 GO evidence and references
  View Computational GO annotations for SAP185
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
181 total interaction(s) for 129 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 85
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 4
  • Biochemical Activity: 2
  • PCA: 1
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 2
  • Dosage Rescue: 1
  • Negative Genetic: 59
  • Positive Genetic: 10
  • Synthetic Growth Defect: 6
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,058
Molecular Weight (Da) 121,401
Isoelectric Point (pI) 4.13
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:242082 to 245258 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3177 242082..245258 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003634
References cited on this page View Complete Literature Guide for SAP185
1) Luke MM, et al.  (1996) The SAP, a new family of proteins, associate and function positively with the SIT4 phosphatase. Mol Cell Biol 16(6):2744-55
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61