| Standard Name | IRC18 1 |
|---|---|
| Systematic Name | YJL037W |
| Feature Type | ORF, Verified |
| Description | Putative protein of unknown function; expression induced in respiratory-deficient cells and in carbon-limited chemostat cultures; similar to adjacent ORF, YJL038C; null mutant displays increased levels of spontaneous Rad52p foci (1, 2, 3, 4, 5, 6) |
| Name Description | Increased Recombination Centers 1 |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All IRC18 GO evidence and references
| View Computational GO annotations for IRC18 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated |
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| Cellular Component | |
| Manually curated |
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Mutant phenotypes All IRC18 Phenotype evidence and references
| Large-scale survey | |
|---|---|
| null | |
| Resources |
interactions All IRC18 Interaction evidence and references
| 5 total interaction(s) for 5 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All IRC18 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000003574 |
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References cited on this page View Complete Literature Guide for IRC18
| 1) | Alvaro D, et al. (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228 |
| 2) | Roberts CJ, et al. (2000) Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science 287(5454):873-80 |
| 3) | Chu S, et al. (1998) The transcriptional program of sporulation in budding yeast. Science 282(5389):699-705 |
| 4) | Primig M, et al. (2000) The core meiotic transcriptome in budding yeasts. Nat Genet 26(4):415-23 |
| 5) | Epstein CB, et al. (2001) Genome-wide responses to mitochondrial dysfunction. Mol Biol Cell 12(2):297-308 |
| 6) | Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 |





