CCT3/YJL014W Summary Help

Standard Name CCT3
Systematic Name YJL014W
Alias BIN2 , TCP3
Feature Type ORF, Verified
Description Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; capable of binding Q/N rich proteins and mediating their folding (1, 2, 3)
Name Description Chaperonin Containing TCP-1
Chromosomal Location
ChrX:407558 to 409162 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CCT3 GO evidence and references
  View Computational GO annotations for CCT3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
reduction of function
Resources
139 total interaction(s) for 111 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 107
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 9
  • Co-fractionation: 1
  • Co-purification: 7

Genetic Interactions
  • Dosage Rescue: 6
  • Synthetic Lethality: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 534
Molecular Weight (Da) 58,814
Isoelectric Point (pI) 6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:407558 to 409162 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1605 407558..409162 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003551
References cited on this page View Complete Literature Guide for CCT3
1) Chen X, et al.  (1994) Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci U S A 91(19):9111-5
2) Vinh DB and Drubin DG  (1994) A yeast TCP-1-like protein is required for actin function in vivo. Proc Natl Acad Sci U S A 91(19):9116-20
3) Nadler-Holly M, et al.  (2012) Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis. Proc Natl Acad Sci U S A 109(46):18833-8