Standard Name	MAL12
Systematic Name	YGR292W
Feature Type	ORF, Verified
Description	Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose (1, 2, 3) Also known as: MALS 4
Name Description	MALtose fermentation

Chromosomal Location	ChrVII:1076599 to 1078353 | ORF Map | GBrowse
	Genetic position: 226 cM

	View Computational GO annotations for MAL12
Molecular Function
Manually curated	maltose alpha-glucosidase activity (IDA) sucrose alpha-glucosidase activity (IDA)
Biological Process
Manually curated	maltose catabolic process (IGI) sucrose catabolic process (IGI)
Cellular Component
High-throughput	plasma membrane (IDA)

Classical genetics
conditional	utilization of carbon source: absent
Large-scale survey
null	competitive fitness: decreased haploinsufficient
overexpression	resistance to sirolimus: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	74 total interaction(s) for 72 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Biochemical Activity: 1 Reconstituted Complex: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 53 Phenotypic Enhancement: 1 Positive Genetic: 12 Synthetic Growth Defect: 2 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:1076599 to 1078353 | ORF Map | GBrowse
	This feature is contained within: MAL1
	Genetic position: 226 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1755 1076599..1078353 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain Kyokai7 S.c. Strain Sigma1278b S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003524