RNH70/YGR276C Summary Help

Standard Name RNH70 1
Systematic Name YGR276C
Alias REX1 2 , RNA82 3
Feature Type ORF, Verified
Description 3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts (2)
Name Description RNase H 1
Chromosomal Location
ChrVII:1045480 to 1043819 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RNH70 GO evidence and references
  View Computational GO annotations for RNH70
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
90 total interaction(s) for 74 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 26

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 34
  • Phenotypic Enhancement: 3
  • Phenotypic Suppression: 2
  • Positive Genetic: 5
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 553
Molecular Weight (Da) 62,849
Isoelectric Point (pI) 7.21
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:1045480 to 1043819 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1662 1045480..1043819 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003508
References cited on this page View Complete Literature Guide for RNH70
1) Frank P, et al.  (1999) Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene. FEBS Lett 450(3):251-6
2) van Hoof A, et al.  (2000) Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J 19(6):1357-65
3) Piper PW, et al.  (1984) Processing of the 3' sequence extensions upon the 5S rRNA of a mutant yeast in Xenopus laevis germinal vesicle extract. Eur J Biochem 141(1):115-8