Standard Name	RNH70 1
Systematic Name	YGR276C
Alias	REX1 2 , RNA82 3
Feature Type	ORF, Verified
Description	3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts (2)
Name Description	RNase H 1

Chromosomal Location	ChrVII:1045480 to 1043819 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RNH70
Molecular Function
Manually curated	3'-5' exonuclease activity (ISS) 3'-5'-exoribonuclease activity (IMP)
Biological Process
Manually curated	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IGI) generation of mature 3'-end of 5S rRNA generated by RNA polymerase III (IMP) tRNA 3'-trailer cleavage, exonucleolytic (IGI, IMP) U5 snRNA 3'-end processing (IGI)
Cellular Component
Manually curated	nucleus (IDA)

Classical genetics
null	viable
Large-scale survey
null	cell cycle progression in G1 phase: increased duration competitive fitness: decreased resistance to benzo[a]pyrene: decreased stress resistance: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	88 total interaction(s) for 74 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Biochemical Activity: 26
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 34 Phenotypic Enhancement: 3 Phenotypic Suppression: 2 Positive Genetic: 6 Synthetic Growth Defect: 8 Synthetic Lethality: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:1045480 to 1043819 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1662 1045480..1043819 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003508