LSC2/YGR244C Summary Help

Standard Name LSC2 1
Systematic Name YGR244C
Feature Type ORF, Verified
Description Beta subunit of succinyl-CoA ligase; succinyl-CoA ligase is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate (1)
Name Description Ligase of Succinyl-CoA 1
Chromosomal Location
ChrVII:979319 to 978036 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All LSC2 GO evidence and references
  View Computational GO annotations for LSC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 9 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
overexpression
Resources
103 total interaction(s) for 71 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 3
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 76
  • Phenotypic Suppression: 1
  • Positive Genetic: 9
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 427
Molecular Weight (Da) 46,900
Isoelectric Point (pI) 7.49
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:979319 to 978036 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1284 979319..978036 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003476
References cited on this page View Complete Literature Guide for LSC2
1) Przybyla-Zawislak B, et al.  (1998) Genes of succinyl-CoA ligase from Saccharomyces cerevisiae. Eur J Biochem 258(2):736-43