SER2/YGR208W Summary Help

Standard Name SER2 1
Systematic Name YGR208W
Feature Type ORF, Verified
Description Phosphoserine phosphatase of the phosphoglycerate pathway; involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source (2, 3)
Name Description SERine requiring 2
Chromosomal Location
ChrVII:911883 to 912812 | ORF Map | GBrowse
Gbrowse
Genetic position: 168 cM
Gene Ontology Annotations All SER2 GO evidence and references
  View Computational GO annotations for SER2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Pathways
Classical genetics
null
reduction of function
Large-scale survey
null
overexpression
Resources
211 total interaction(s) for 162 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 4
  • PCA: 3

Genetic Interactions
  • Negative Genetic: 169
  • Positive Genetic: 14
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 8
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 309
Molecular Weight (Da) 34,207
Isoelectric Point (pI) 4.92
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:911883 to 912812 | ORF Map | GBrowse
SGD ORF map
Genetic position: 168 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..930 911883..912812 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003440
References cited on this page View Complete Literature Guide for SER2
1) Song, J.M., et al.  (1995) Identification and characterization of the Saccharomyces cerevisiae SER2 Gene. Unpublished
2) Melcher K and Entian KD  (1992) Genetic analysis of serine biosynthesis and glucose repression in yeast. Curr Genet 21(4-5):295-300
3) Albers E, et al.  (2003) Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. J Biol Chem 278(12):10264-72