CRH1/YGR189C Summary Help

CRH1 BASIC INFORMATION

Standard Name CRH1 1
Systematic Name YGR189C
Feature Type ORF, Verified
Description Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress (1, 2, 3, 4, 5)
Name Description Congo Red Hypersensitive 1
GO Annotations All CRH1 GO evidence and references
    View Computational GO annotations for CRH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All CRH1 Phenotype details and references
Classical genetics
null
overexpression
Large-scale survey
null
Interactions CRH1 All interactions details and references
7 total interaction(s) for 6 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1
  • Two-hybrid: 1
Genetic Interactions
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 3
Sequence Information
ChrVII:878197 to 876674 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1524 878197..876674 2004-07-20 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003421

CRH1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for CRH1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CRH1]

1) Rodriguez-Pena JM, et al.  (2000) A novel family of cell wall-related proteins regulated differently during the yeast life cycle. Mol Cell Biol 20(9):3245-55
2) Cabib E, et al.  (2007) Crh1p and Crh2p are required for the cross-linking of chitin to beta(1-6)glucan in the Saccharomyces cerevisiae cell wall. Mol Microbiol 63(3):921-35
3) Bermejo C, et al.  (2008) The Sequential Activation of the Yeast HOG and SLT2 Pathways Is Required for Cell Survival to Cell Wall Stress. Mol Biol Cell 19(3):1113-24
4) Cabib E, et al.  (2008) Assembly of the Yeast Cell Wall: Crh1p AND Crh2p ACT AS TRANSGLYCOSYLASES IN VIVO AND IN VITRO. J Biol Chem 283(44):29859-72
5) Cabib E  (2009) Two novel techniques for determination of polysaccharide cross-links show that Crh1p and Crh2p attach chitin to both beta(1-6)- and beta(1-3)glucan in the Saccharomyces cerevisiae cell wall. Eukaryot Cell 8(11):1626-36