Standard Name	PTI1 1
Systematic Name	YGR156W
Feature Type	ORF, Verified
Description	Essential protein that is a component of CPF (cleavage and polyadenylation factor); involved in 3' end formation of snoRNA and mRNA; interacts directly with Pta1p; has similarity to mammalian Cleavage-Stimulation Factor CstF-64 (1, 2, 3)
Name Description	PTa1p Interacting protein 1

Chromosomal Location	ChrVII:800546 to 801823 | ORF Map | GBrowse

	View Computational GO annotations for PTI1
Molecular Function
Manually curated	contributes_to RNA binding (IC)
Biological Process
Manually curated	mRNA cleavage (IMP, IPI) mRNA polyadenylation (IMP, IPI) snoRNA 3'-end processing (IMP) termination of RNA polymerase II transcription, exosome-dependent (IMP, IPI) termination of RNA polymerase II transcription, poly(A)-coupled (IPI)
Cellular Component
Manually curated	mRNA cleavage and polyadenylation specificity factor complex (IDA)
High-throughput	nucleus (IDA)

Large-scale survey
conditional	chromosome/plasmid maintenance: abnormal colony sectoring: increased
null	inviable
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	113 total interaction(s) for 46 unique genes/features.
Physical Interactions	Affinity Capture-MS: 76 Affinity Capture-RNA: 3 Affinity Capture-Western: 3 Far Western: 3 Reconstituted Complex: 1 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 17 Positive Genetic: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:800546 to 801823 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1278 800546..801823 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003388