CAF130/YGR134W Summary Help

Standard Name CAF130 1
Systematic Name YGR134W
Feature Type ORF, Verified
Description Subunit of the CCR4-NOT transcriptional regulatory complex; CCR4-NOT complex is evolutionarily-conserved and involved in controlling mRNA initiation, elongation, and degradation (1)
Name Description CCR4 Associated Factor 1
Chromosomal Location
ChrVII:757770 to 761138 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CAF130 GO evidence and references
  View Computational GO annotations for CAF130
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
97 total interaction(s) for 61 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 12
  • Co-purification: 1
  • Two-hybrid: 5

Genetic Interactions
  • Negative Genetic: 30
  • Positive Genetic: 10
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 4
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,122
Molecular Weight (Da) 128,779
Isoelectric Point (pI) 4.82
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:757770 to 761138 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3369 757770..761138 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003366
References cited on this page View Complete Literature Guide for CAF130
1) Chen J, et al.  (2001) Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. J Mol Biol 314(4):683-94