FHN1/YGR131W Summary Help

Standard Name FHN1 1
Systematic Name YGR131W
Feature Type ORF, Verified
Description Protein of unknown function; induced by ketoconazole; promoter region contains sterol regulatory element motif, which has been identified as a Upc2p-binding site; overexpression complements function of Nce102p in NCE102 deletion strain; FHN1 has a paralog, NCE102, that arose from the whole genome duplication (1, 2, 3)
Name Description Functional Homologue of Nce102 1
Chromosomal Location
ChrVII:754726 to 755250 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All FHN1 GO evidence and references
Molecular Function
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Large-scale survey
null
overexpression
Resources
3 total interaction(s) for 3 unique genes/features.
Physical Interactions
  • Two-hybrid: 1

Genetic Interactions
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 174
Molecular Weight (Da) 19,152
Isoelectric Point (pI) 10.67
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:754726 to 755250 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..525 754726..755250 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003363
References cited on this page View Complete Literature Guide for FHN1
1) Loibl M, et al.  (2010) C Terminus of Nce102 Determines the Structure and Function of Microdomains in the Saccharomyces cerevisiae Plasma Membrane. Eukaryot Cell 9(8):1184-92
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Agarwal AK, et al.  (2003) Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. J Biol Chem 278(37):34998-5015