NOP7/YGR103W Summary Help

NOP7 BASIC INFORMATION

Standard Name NOP7 1
Systematic Name YGR103W
Alias YPH1 2
Feature Type ORF, Verified
Description Component of several different pre-ribosomal particles; forms a complex with Ytm1p and Erb1p that is required for maturation of the large ribosomal subunit; required for exit from G0 and the initiation of cell proliferation (1, 3, 4, 5)
Name Description NucleOlar Protein 1
GO Annotations All NOP7 GO evidence and references
    View Computational GO annotations for NOP7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All NOP7 Phenotype details and references
Large-scale survey
null
overexpression
Interactions NOP7 All interactions details and references
281 total interaction(s) for 109 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 223
  • Affinity Capture-Western: 41
  • Co-purification: 3
  • PCA: 2
  • Reconstituted Complex: 4
  • Two-hybrid: 2
Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 1
  • Synthetic Lethality: 3
Sequence Information
ChrVII:695421 to 697238 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1818 695421..697238 2004-07-20 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003335

NOP7 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for NOP7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NOP7]

1) Harnpicharnchai P, et al.  (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
2) Sakumoto N, et al.  (2001) Dual-specificity protein phosphatase Yvh1p, which is required for vegetative growth and sporulation, interacts with yeast pescadillo homolog in Saccharomyces cerevisiae. Biochem Biophys Res Commun 289(2):608-15
3) Oeffinger M, et al.  (2002) Yeast Pescadillo is required for multiple activities during 60S ribosomal subunit synthesis. RNA 8(5):626-36
4) Du YC and Stillman B  (2002) Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis. Cell 109(7):835-48
5) Miles TD, et al.  (2005) Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes. Mol Cell Biol 25(23):10419-32