PRP31/YGR091W Summary

PRP31 BASIC INFORMATION

Standard Name	PRP31 1
Systematic Name	YGR091W
Feature Type	ORF, Verified
Description	Splicing factor, component of the U4/U6-U5 snRNP complex (2)
Name Description	Pre-mRNA Processing 3

GO Annotations	All PRP31 GO evidence and references
	View Computational GO annotations for PRP31
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	nuclear mRNA splicing, via spliceosome (IPI) spliceosomal snRNP assembly (IDA, IMP)
Cellular Component
Manually curated	U4/U6 x U5 tri-snRNP complex (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All PRP31 Phenotype details and references
Large-scale survey
null	inviable
overexpression	cell cycle progression: abnormal
repressible	mitochondrial morphology: abnormal

Interactions	PRP31 All interactions details and references
	128 total interaction(s) for 61 unique genes/features.
Physical Interactions	Affinity Capture-MS: 110 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Co-purification: 3 Two-hybrid: 5
Genetic Interactions	Phenotypic Enhancement: 4 Phenotypic Suppression: 4

Sequence Information

ChrVII:666345 to 667829 | |

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1485	666345..667829	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003323

PRP31 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PRP31

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRP31]

1)	Maddock JR, et al. (1996) Six novel genes necessary for pre-mRNA splicing in Saccharomyces cerevisiae. Nucleic Acids Res 24(6):1037-44
2)	Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31
3)	Vijayraghavan U, et al. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16

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