ROM1/YGR070W Summary

ROM1 BASIC INFORMATION

Standard Name	ROM1 1, 2
Systematic Name	YGR070W
Alias	SKC1
Feature Type	ORF, Verified
Description	GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP (1)
Name Description	RhO1 Multicopy suppressor 1

GO Annotations	All ROM1 GO evidence and references
	View Computational GO annotations for ROM1
Molecular Function
Manually curated	Rho guanyl-nucleotide exchange factor activity (ISA) signal transducer activity (TAS)
Biological Process
Manually curated	actin filament organization (TAS) budding cell bud growth (TAS) establishment of cell polarity (TAS) fungal-type cell wall organization (TAS) small GTPase mediated signal transduction (TAS)
Cellular Component
Manually curated	intracellular (TAS)

Mutant Phenotype	All ROM1 Phenotype details and references
Large-scale survey
null	UV resistance: decreased filamentous growth: decreased invasive growth: absent resistance to oleate: decreased viable

Interactions	ROM1 All interactions details and references
	12 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 2 Phenotypic Enhancement: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 3 Synthetic Rescue: 2

Sequence Information

ChrVII:627810 to 631277 | |

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3468	627810..631277	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003302

ROM1 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ROM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ROM1]

1)	Ozaki K, et al. (1996) Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 15(9):2196-207
2)	Jacoby, J.J. et al. (1996) Isolation of a novel pkc1 mutant and two of its multicopy suppressors from Saccharomyces cerevisiae. Unpublished

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.