VHT1/YGR065C Summary Help

Standard Name VHT1 1
Systematic Name YGR065C
Feature Type ORF, Verified
Description High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin (1, 2)
Name Description Vitamin H Transporter 1
Chromosomal Location
ChrVII:619858 to 618077 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All VHT1 GO evidence and references
  View Computational GO annotations for VHT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
overexpression
unspecified
Large-scale survey
null
reduction of function
Resources
20 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • PCA: 9

Genetic Interactions
  • Negative Genetic: 6
  • Positive Genetic: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 593
Molecular Weight (Da) 69,082
Isoelectric Point (pI) 9.34
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:619858 to 618077 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1782 619858..618077 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003297
References cited on this page View Complete Literature Guide for VHT1
1) Stolz J, et al.  (1999) Identification of the plasma membrane H+-biotin symporter of Saccharomyces cerevisiae by rescue of a fatty acid-auxotrophic mutant. J Biol Chem 274(26):18741-6
2) Shakoury-Elizeh M, et al.  (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43