ADE6/YGR061C Summary Help

Standard Name ADE6
Systematic Name YGR061C
Feature Type ORF, Verified
Description Formylglycinamidine-ribonucleotide (FGAM)-synthetase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway (1, 2)
Name Description ADEnine requiring
Chromosomal Location
ChrVII:615965 to 611889 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 39 cM
Gene Ontology Annotations All ADE6 GO evidence and references
  View Computational GO annotations for ADE6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
77 total interaction(s) for 54 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 2
  • Co-purification: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 43
  • Phenotypic Suppression: 2
  • Positive Genetic: 13
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,358
Molecular Weight (Da) 148,904
Isoelectric Point (pI) 5.02
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:615965 to 611889 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 39 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4077 615965..611889 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003293
References cited on this page View Complete Literature Guide for ADE6
1) Andreichuk YuV, et al.  (1997) ADE6 gene of Saccharomyces cerevisiae yeast encoding formylglycinamidine-ribonucleotide synthetase. Cloning, sequencing, and analysis. Biochemistry (Mosc) 62(7):742-52
2) Jones EW and Fink GR  (1982) "Regulation of amino acid and nucleotide biosynthesis in yeast." Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press