SCM4/YGR049W Summary Help

Standard Name SCM4 1
Systematic Name YGR049W
Feature Type ORF, Verified
Description Mitochondrial outer membrane protein of unknown function; predicted to have 4 transmembrane segments; import is mediated by Tom70p and Mim1p; interacts genetically with a cdc4 mutation; SCM4 has a paralog, ATG33, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Suppressor of Cdc4 Mutation 1
Chromosomal Location
ChrVII:591314 to 591877 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SCM4 GO evidence and references
  View Computational GO annotations for SCM4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 5 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
overexpression
Resources
7 total interaction(s) for 6 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 187
Molecular Weight (Da) 20,118
Isoelectric Point (pI) 8.54
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:591314 to 591877 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..564 591314..591877 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003281
References cited on this page View Complete Literature Guide for SCM4
1) Smith SA, et al.  (1992) SCM4, a gene that suppresses mutant cdc4 function in budding yeast. Mol Gen Genet 235(2-3):285-91
2) Sherlock G and Rosamond J  (1993) Starting to cycle: G1 controls regulating cell division in budding yeast. J Gen Microbiol 139(11):2531-41
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Becker T, et al.  (2011) The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. J Cell Biol 194(3):387-95