SWC4/YGR002C Summary Help

SWC4 BASIC INFORMATION

Standard Name SWC4 1
Systematic Name YGR002C
Alias EAF2 2 , GOD1
Feature Type ORF, Verified
Description Component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex (2, 3, 4, 5, 6)
Name Description SWr Complex
GO Annotations All SWC4 GO evidence and references
    View Computational GO annotations for SWC4
Molecular Function
High-throughput
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All SWC4 Phenotype details and references
Classical genetics
conditional
null
reduction of function
repressible
Large-scale survey
conditional
null
Interactions SWC4 All interactions details and references
317 total interaction(s) for 203 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 82
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 15
  • Co-purification: 1
  • Two-hybrid: 2
Genetic Interactions
  • Synthetic Growth Defect: 106
  • Synthetic Lethality: 107
  • Synthetic Rescue: 3
Sequence Information
ChrVII:499910 to 498480 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1431 499910..498480 2004-07-20 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003234

SWC4 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SWC4

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SWC4]

1) Schaft, D, et al.  (2002) personal communication
2) Nourani A, et al.  (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5
3) Eisen A, et al.  (2001) The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation. J Biol Chem 276(5):3484-91
4) Nourani A, et al.  (2001) Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex. Mol Cell Biol 21(22):7629-40
5) Krogan NJ, et al.  (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76
6) Mizuguchi G, et al.  (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8