STR3/YGL184C Summary Help

Standard Name STR3 1
Systematic Name YGL184C
Feature Type ORF, Verified
Description Peroxisomal cystathionine beta-lyase; converts cystathionine into homocysteine; may be redox regulated by Gto1p; involved in the release of the aromatic thiol 3-mercaptohexanol during wine fermentation (1, 2, 3, 4)
Name Description Sulfur TRansfer
Chromosomal Location
ChrVII:156012 to 154615 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All STR3 GO evidence and references
  View Computational GO annotations for STR3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 17 genes
Resources
Pathways
Classical genetics
null
overexpression
Large-scale survey
null
repressible
Resources
32 total interaction(s) for 31 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Biochemical Activity: 4
  • Protein-peptide: 3
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 20
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 465
Molecular Weight (Da) 51,828
Isoelectric Point (pI) 7.96
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:156012 to 154615 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1398 156012..154615 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003152
References cited on this page View Complete Literature Guide for STR3
1) Hansen J and Johannesen PF  (2000) Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet 263(3):535-42
2) Barreto L, et al.  (2006) A Peroxisomal Glutathione Transferase of Saccharomyces cerevisiae Is Functionally Related to Sulfur Amino Acid Metabolism. Eukaryot Cell 5(10):1748-59
3) Schafer H, et al.  (2001) Identification of peroxisomal membrane proteins of Saccharomyces cerevisiae by mass spectrometry. Electrophoresis 22(14):2955-68
4) Holt S, et al.  (2011) Engineering Saccharomyces cerevisiae to release 3-Mercaptohexan-1-ol during fermentation through overexpression of an S. cerevisiae Gene, STR3, for improvement of wine aroma. Appl Environ Microbiol 77(11):3626-32