Standard Name	AMS1 1
Systematic Name	YGL156W
Feature Type	ORF, Verified
Description	Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway (2, 3, 4)
Name Description	Alpha-MannoSidase 1

Chromosomal Location	ChrVII:210416 to 213667 | ORF Map | GBrowse
	Genetic position: -98 cM

	View Computational GO annotations for AMS1
Molecular Function
Manually curated	alpha-mannosidase activity (IDA, ISS)
Biological Process
Manually curated	cellular carbohydrate metabolic process (ISS) oligosaccharide catabolic process (IMP)
Cellular Component
Manually curated	fungal-type vacuole membrane (IDA)

Classical genetics
null	Hex(5-6)HexNAc2 accumulation: absent
unspecified	transposable element transposition: decreased
Large-scale survey
null	competitive fitness: decreased metal resistance: decreased resistance to citric acid: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	23 total interaction(s) for 16 unique genes/features.
Physical Interactions	Affinity Capture-MS: 7 Affinity Capture-RNA: 1 Affinity Capture-Western: 3 Co-fractionation: 1 Two-hybrid: 5
Genetic Interactions	Dosage Growth Defect: 1 Negative Genetic: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:210416 to 213667 | ORF Map | GBrowse
	Genetic position: -98 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..3252 210416..213667 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003124