CDC43/YGL155W Summary Help

Standard Name CDC43 1, 2
Systematic Name YGL155W
Alias CAL1
Feature Type ORF, Verified
Description Beta subunit of geranylgeranyltransferase type I; catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis (3)
Name Description Cell Division Cycle 1
Chromosomal Location
ChrVII:214081 to 215211 | ORF Map | GBrowse
Gbrowse
Genetic position: -99 cM
Gene Ontology Annotations All CDC43 GO evidence and references
  View Computational GO annotations for CDC43
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
conditional
Large-scale survey
null
repressible
Resources
58 total interaction(s) for 47 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 17
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 29
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 376
Molecular Weight (Da) 42,689
Isoelectric Point (pI) 6.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:214081 to 215211 | ORF Map | GBrowse
SGD ORF map
Genetic position: -99 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1131 214081..215211 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003123
References cited on this page View Complete Literature Guide for CDC43
1) Adams AE, et al.  (1990) CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol 111(1):131-42
2) Adams, A. and Pringle, J.  (1985) Personal Communication, Mortimer Map Edition 9
3) Stirtan WG and Poulter CD  (1997) Yeast protein geranylgeranyltransferase type-I: steady-state kinetics and substrate binding. Biochemistry 36(15):4552-7