| Standard Name | CDC43 1, 2 (see Nomenclature conflict Note) |
|---|---|
| Systematic Name | YGL155W |
| Alias | CAL1 |
| Feature Type | ORF, Verified |
| Description | Beta subunit of geranylgeranyltransferase type I, catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis (3) |
| Name Description | Cell Division Cycle 1 |
| Chromosomal Location | |
|---|---|
| Genetic position: -99 cM |
Gene Ontology Annotations All CDC43 GO evidence and references
| View Computational GO annotations for CDC43 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All CDC43 Phenotype evidence and references
| Classical genetics | |
|---|---|
| conditional |
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| Large-scale survey | |
| null | |
| repressible | |
| Resources |
interactions All CDC43 Interaction evidence and references
| 53 total interaction(s) for 45 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All CDC43 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Genetic position: -99 cM | |||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
|---|
| Primary SGDID | S000003123 |
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NOMENCLATURE CONFLICT NOTE
| Name | Relevance | Description |
|---|---|---|
| CHS3 | Nomenclature conflict | CAL1 has been used to refer to both CDC43/YGL155W, which encodes a subunit of protein geranylgeranyltransferase, and CHS3/YBR023C, which encodes chitin synthase 3. |
References cited on this page View Complete Literature Guide for CDC43
| 1) | Adams AE, et al. (1990) CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol 111(1):131-42 |
| 2) | Adams, A. and Pringle, J. (1985) Personal Communication, Mortimer Map Edition 9 |
| 3) | Stirtan WG and Poulter CD (1997) Yeast protein geranylgeranyltransferase type-I: steady-state kinetics and substrate binding. Biochemistry 36(15):4552-7 |




