LYS5/YGL154C Summary Help

Standard Name LYS5 1
Systematic Name YGL154C
Feature Type ORF, Verified
Description Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine (2)
Name Description LYSine requiring 1
Chromosomal Location
ChrVII:216096 to 215278 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -97 cM
Gene Ontology Annotations All LYS5 GO evidence and references
  View Computational GO annotations for LYS5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
reduction of function
unspecified
Large-scale survey
null
overexpression
Resources
9 total interaction(s) for 6 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Two-hybrid: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 272
Molecular Weight (Da) 30,683
Isoelectric Point (pI) 4.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:216096 to 215278 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -97 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..819 216096..215278 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003122
References cited on this page View Complete Literature Guide for LYS5
1) Miller KG and Bhattacharjee JK  (1996) The LYS5 gene of Saccharomyces cerevisiae. Gene 172(1):167-8
2) Ehmann DE, et al.  (1999) Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5. Biochemistry 38(19):6171-7