GPI10/YGL142C Summary Help

Standard Name GPI10 1
Systematic Name YGL142C
Feature Type ORF, Verified
Description Integral membrane protein involved in GPI anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the glycosylphosphatidylinositol (GPI) core structure; human PIG-Bp is a functional homolog (1, 2)
Name Description GlycosylPhosphatidylInositol anchor biosynthesis 1, 2
Chromosomal Location
ChrVII:238119 to 236269 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All GPI10 GO evidence and references
  View Computational GO annotations for GPI10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
conditional
null
overexpression
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
10 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 616
Molecular Weight (Da) 72,565
Isoelectric Point (pI) 8.75
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:238119 to 236269 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1851 238119..236269 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003110
References cited on this page View Complete Literature Guide for GPI10
1) Sutterlin C, et al.  (1998) Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis. Biochem J 332 ( Pt 1)():153-9
2) Canivenc-Gansel E, et al.  (1998) GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the alpha1,4-linked mannose of the complete precursor glycophospholipid. Glycobiology 8(8):761-70