VPS73/YGL104C Summary Help

Standard Name VPS73 1
Systematic Name YGL104C
Feature Type ORF, Verified
Description Mitochondrial protein; mutation affects vacuolar protein sorting; putative transporter; member of the sugar porter family; VPS73 has a paralog, YBR241C, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Vacuolar Protein Sorting 1
Chromosomal Location
ChrVII:310173 to 308713 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All VPS73 GO evidence and references
  View Computational GO annotations for VPS73
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
44 total interaction(s) for 42 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • PCA: 20
  • Two-hybrid: 7

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 1
  • Synthetic Growth Defect: 6
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 486
Molecular Weight (Da) 54,331
Isoelectric Point (pI) 9.73
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:310173 to 308713 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1461 310173..308713 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003072
References cited on this page View Complete Literature Guide for VPS73
1) Bonangelino CJ, et al.  (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13(7):2486-501
2) Sickmann A, et al.  (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Palma M, et al.  (2007) A phylogenetic analysis of the sugar porters in hemiascomycetous yeasts. J Mol Microbiol Biotechnol 12(3-4):241-8