USE1/YGL098W Summary Help

Standard Name USE1 1
Systematic Name YGL098W
Alias SLT1 2
Feature Type ORF, Verified
Description Essential SNARE protein localized to the ER; involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p (1, 2)
Name Description Unconventional SNARE in the ER 1
Chromosomal Location
ChrVII:317342 to 318079 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All USE1 GO evidence and references
  View Computational GO annotations for USE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
conditional
null
Large-scale survey
conditional
null
reduction of function
repressible
Resources
116 total interaction(s) for 72 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 18
  • Co-fractionation: 2
  • Co-purification: 1
  • PCA: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 7

Genetic Interactions
  • Negative Genetic: 45
  • Positive Genetic: 2
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 245
Molecular Weight (Da) 28,106
Isoelectric Point (pI) 5.01
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:317342 to 318079 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..738 317342..318079 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003066
References cited on this page View Complete Literature Guide for USE1
1) Dilcher M, et al.  (2003) Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J 22(14):3664-74
2) Burri L, et al.  (2003) A SNARE required for retrograde transport to the endoplasmic reticulum. Proc Natl Acad Sci U S A 100(17):9873-7