TOS8/YGL096W Summary

TOS8 BASIC INFORMATION

Standard Name	TOS8 1
Systematic Name	YGL096W
Feature Type	ORF, Verified
Description	Homeodomain-containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; similar to Cup9p transcription factor (1)
Name Description	Target Of Sbf 1

GO Annotations	All TOS8 GO evidence and references
	View Computational GO annotations for TOS8
Molecular Function
Manually curated	chromatin binding (IDA)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	nuclear chromatin (IDA)

Regulatory Role
Regulatory modules	predicted: stressResponse ( 643 , 637 , 493 , 427 )

Mutant Phenotype	All TOS8 Phenotype details and references
Classical genetics
null	viable
Large-scale survey
null	sporulation: normal viable
overexpression	vegetative growth: decreased

Interactions	TOS8 All interactions details and references
	7 total interaction(s) for 6 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Two-hybrid: 4
Genetic Interactions	Synthetic Growth Defect: 1

Sequence Information

ChrVII:325334 to 326164 | |

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..831	325334..326164	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003064

TOS8 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for TOS8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TOS8]

1)	Horak CE, et al. (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33

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