DBP3/YGL078C Summary

DBP3 BASIC INFORMATION

Standard Name	DBP3
Systematic Name	YGL078C
Feature Type	ORF, Verified
Description	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis (1)
Name Description	Dead Box Protein

GO Annotations	All DBP3 GO evidence and references
	View Computational GO annotations for DBP3
Molecular Function
Manually curated	ATP-dependent RNA helicase activity (TAS) RNA-dependent ATPase activity (IDA)
Biological Process
Manually curated	ribosomal large subunit assembly (IMP) rRNA processing (IMP)
Cellular Component
Manually curated	nucleolus (IDA)

Mutant Phenotype	All DBP3 Phenotype details and references
Large-scale survey
null	acid pH resistance: decreased competitive fitness: decreased fermentative growth: decreased rate filamentous growth: decreased invasive growth: absent replicative lifespan: increased resistance to doxorubicin: decreased resistance to 5-fluorouracil: decreased toxin resistance: increased transposable element transposition: decreased viable
overexpression	vegetative growth: decreased

Interactions	DBP3 All interactions details and references
	81 total interaction(s) for 69 unique genes/features.
Physical Interactions	Affinity Capture-MS: 25 Affinity Capture-Western: 2 PCA: 4
Genetic Interactions	Phenotypic Enhancement: 13 Phenotypic Suppression: 32 Synthetic Growth Defect: 3 Synthetic Lethality: 1 Synthetic Rescue: 1

Sequence Information

ChrVII:361862 to 360291 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1572	361862..360291	2004-07-20	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003046

DBP3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DBP3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DBP3]

1)	Weaver PL, et al. (1997) Dbp3p, a putative RNA helicase in Saccharomyces cerevisiae, is required for efficient pre-rRNA processing predominantly at site A3. Mol Cell Biol 17(3):1354-65

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