COG7/YGL005C Summary

COG7 BASIC INFORMATION

Standard Name	COG7 1
Systematic Name	YGL005C
Alias	COD5
Feature Type	ORF, Verified
Description	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments (1, 2)
Name Description	Conserved Oligomeric Golgi complex 1

GO Annotations	All COG7 GO evidence and references
	View Computational GO annotations for COG7
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	intra-Golgi vesicle-mediated transport (IGI, IPI)
Cellular Component
Manually curated	Golgi transport complex (IPI)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All COG7 Phenotype details and references
Large-scale survey
null	resistance to hygromycin B: decreased viable
overexpression	filamentous growth: increased

Interactions	COG7 All interactions details and references
	128 total interaction(s) for 62 unique genes/features.
Physical Interactions	Affinity Capture-MS: 21 Affinity Capture-RNA: 1 Affinity Capture-Western: 9 Biochemical Activity: 1 Protein-RNA: 1 Two-hybrid: 2
Genetic Interactions	Phenotypic Enhancement: 72 Phenotypic Suppression: 2 Synthetic Growth Defect: 6 Synthetic Lethality: 13

Sequence Information

ChrVII:490551 to 489712 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..840	490551..489712	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002973

COG7 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for COG7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for COG7]

1)	Ram RJ, et al. (2002) Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell 13(5):1484-500
2)	Loh E and Hong W (2004) The binary interacting network of the conserved oligomeric Golgi tethering complex. J Biol Chem 279(23):24640-8

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.