Standard Name	RPN14 1
Systematic Name	YGL004C
Feature Type	ORF, Verified
Description	Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p (1, 2, 3, 4, 5, 6)
Name Description	Regulatory Particle Non-ATPase 1

Chromosomal Location	ChrVII:491956 to 490703 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RPN14
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	proteasome regulatory particle assembly (IGI, IMP) ubiquitin-dependent protein catabolic process (IMP)
Cellular Component
Manually curated	cytosol (IDA) nucleus (IDA)
High-throughput	cytoplasm (IDA)

Classical genetics
null	heat sensitivity: increased viable
Large-scale survey
null	competitive fitness: increased resistance to benzo[a]pyrene: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	81 total interaction(s) for 30 unique genes/features.
Physical Interactions	Affinity Capture-MS: 23 Affinity Capture-Western: 29 Co-purification: 1 Reconstituted Complex: 2 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 8 Phenotypic Enhancement: 4 Synthetic Growth Defect: 8 Synthetic Lethality: 1 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:491956 to 490703 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1254 491956..490703 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002972