LSB3/YFR024C-A Summary

LSB3 BASIC INFORMATION

Standard Name	LSB3 1
Systematic Name	YFR024C-A
Alias	YFR024C
Feature Type	ORF, Verified
Description	Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization (1)
Name Description	Las Seventeen Binding protein 1

GO Annotations	All LSB3 GO evidence and references
	View Computational GO annotations for LSB3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	actin cortical patch localization (IGI, IMP)
Cellular Component
High-throughput	cellular bud neck (IDA) cytoplasm (IDA) mitochondrion (IDA)

Mutant Phenotype	All LSB3 Phenotype details and references
Large-scale survey
null	resistance to hygromycin B: decreased viable

Interactions	LSB3 All interactions details and references
	133 total interaction(s) for 96 unique genes/features.
Physical Interactions	Affinity Capture-MS: 23 Affinity Capture-Western: 1 Biochemical Activity: 5 PCA: 8 Protein-peptide: 8 Two-hybrid: 85
Genetic Interactions	Synthetic Growth Defect: 1 Synthetic Lethality: 2

Sequence Information

ChrVI:203421 to 201948 | |

Note: this feature is encoded on the Crick strand.

This feature contains embedded feature(s): YFR024C

Last Update

Coordinates: 2003-09-26 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..47	203421..203375	2003-09-26	1996-07-31
Intron	48..141	203374..203281	2008-06-02	2008-06-02
CDS	142..1474	203280..201948	2008-06-02	2008-06-02

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002968

LSB3 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for LSB3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for LSB3]

1)	Madania A, et al. (1999) The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex. Mol Biol Cell 10(10):3521-38

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.