SPS1/YDR523C Summary Help

Standard Name SPS1 1
Systematic Name YDR523C
Feature Type ORF, Verified
Description Putative protein serine/threonine kinase; expressed at the end of meiosis and localized to the prospore membrane; required for correct localization of enzymes involved in spore wall synthesis (2, 3)
Name Description SPorulation Specific 1
Chromosomal Location
ChrIV:1487038 to 1485566 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SPS1 GO evidence and references
  View Computational GO annotations for SPS1
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
82 total interaction(s) for 82 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 25
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 6
  • Reconstituted Complex: 22
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Growth Defect: 8
  • Negative Genetic: 12
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 490
Molecular Weight (Da) 55,704
Isoelectric Point (pI) 7.65
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1487038 to 1485566 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1473 1487038..1485566 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002931
References cited on this page View Complete Literature Guide for SPS1
1) Percival-Smith A and Segall J  (1986) Characterization and mutational analysis of a cluster of three genes expressed preferentially during sporulation of Saccharomyces cerevisiae. Mol Cell Biol 6(7):2443-51
2) Friesen H, et al.  (1994) Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation. Genes Dev 8(18):2162-75
3) Iwamoto MA, et al.  (2005) Saccharomyces cerevisiae Sps1p regulates trafficking of enzymes required for spore wall synthesis. Eukaryot Cell 4(3):536-44