GNP1/YDR508C Summary Help

GNP1 BASIC INFORMATION

Standard Name GNP1
Systematic Name YDR508C
Feature Type ORF, Verified
Description High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids (1, 2, 3, 4)
Name Description GlutamiNe Permease 2
GO Annotations All GNP1 GO evidence and references
    View Computational GO annotations for GNP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All GNP1 Phenotype details and references
Classical genetics
gain of function
null
Large-scale survey
null
Interactions GNP1 All interactions details and references
17 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1
  • Two-hybrid: 7
Genetic Interactions
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 4
Sequence Information
ChrIV:1468437 to 1466446 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1992 1468437..1466446 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | TCDB | UniProtKB
Primary SGDIDS000002916

GNP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for GNP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GNP1]

1) Regenberg B, et al.  (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28
2) Zhu X, et al.  (1996) GNP1, the high-affinity glutamine permease of S. cerevisiae. Curr Genet 30(2):107-14
3) Forsberg H, et al.  (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28
4) Eckert-Boulet N, et al.  (2005) Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Curr Genet 47(3):139-49