PLM2/YDR501W Summary Help

Standard Name PLM2 1, 2
Systematic Name YDR501W
Feature Type ORF, Verified
Description Putative transcription factor, contains Forkhead Associated domain; found associated with chromatin; target of SBF transcription factor; induced in response to DNA damaging agents and deletion of telomerase; PLM2 has a paralog, TOS4, that arose from the whole genome duplication (2, 3, 4, 5)
Name Description PLasmid Maintenance 1
Chromosomal Location
ChrIV:1451353 to 1452918 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PLM2 GO evidence and references
  View Computational GO annotations for PLM2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
null
Large-scale survey
null
overexpression
Resources
80 total interaction(s) for 79 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 2
  • PCA: 30

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 28
  • Positive Genetic: 16

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1451353 to 1452918 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1566 1451353..1452918 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002909
References cited on this page View Complete Literature Guide for PLM2
1) Duffy, K. and A. Cashmore  (1999) PLM2: A novel gene required for the correct partitioning of the 2mu-m plasmid of the yeast Saccharomyces cerevisiae
2) Huang M and Elledge SJ  (2000) The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway. Cold Spring Harb Symp Quant Biol 65():413-21
3) Horak CE, et al.  (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Nautiyal S, et al.  (2002) The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 99(14):9316-21