Standard Name	KRE2
Systematic Name	YDR483W
Alias	MNT1 1
Feature Type	ORF, Verified
Description	Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication (1, 2)
Name Description	Killer toxin REsistant 3

Chromosomal Location	ChrIV:1421157 to 1422485 | ORF Map | GBrowse
	Genetic position: 306 cM

	View Computational GO annotations for KRE2
Molecular Function
Manually curated	alpha-1,2-mannosyltransferase activity (IDA, ISS)
Biological Process
Manually curated	cell wall mannoprotein biosynthetic process (IMP) N-glycan processing (IMP) protein O-linked glycosylation (IMP)
Cellular Component
Manually curated	Golgi apparatus (IDA)

Classical genetics
null	heat sensitivity: increased N-glycosylated protein modification: abnormal
unspecified	killer toxin resistance: increased resistance to papulacandin B: decreased resistance to enzymatic treatment: decreased
Large-scale survey
null	competitive fitness: decreased resistance to sulfanilamide: decreased resistance to 2,4-Diacetylphloroglucinol: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
unspecified	resistance to Calcofluor White: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	23 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-MS: 8 Affinity Capture-RNA: 2 Affinity Capture-Western: 1 Co-purification: 3 PCA: 1 Reconstituted Complex: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 2 Positive Genetic: 2 Synthetic Growth Defect: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1421157 to 1422485 | ORF Map | GBrowse
	Genetic position: 306 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1329 1421157..1422485 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002891