KRE2/YDR483W Summary

KRE2 BASIC INFORMATION

Standard Name	KRE2
Systematic Name	YDR483W
Alias	MNT1 1
Feature Type	ORF, Verified
Description	Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation (1)
Name Description	Killer toxin REsistant 2

GO Annotations	All KRE2 GO evidence and references
	View Computational GO annotations for KRE2
Molecular Function
Manually curated	alpha-1,2-mannosyltransferase activity (IDA, ISS)
Biological Process
Manually curated	cell wall mannoprotein biosynthetic process (IMP) N-glycan processing (IMP) protein amino acid O-linked glycosylation (IMP)
Cellular Component
Manually curated	Golgi apparatus (ISS)

Mutant Phenotype	All KRE2 Phenotype details and references
Classical genetics
null	heat sensitivity: increased N-glycosylated protein modification: abnormal
Large-scale survey
null	resistance to sulfanilamide: decreased viable

Interactions	KRE2 All interactions details and references
	19 total interaction(s) for 14 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Co-purification: 3 Reconstituted Complex: 2 Two-hybrid: 2
Genetic Interactions	Phenotypic Enhancement: 2 Phenotypic Suppression: 2 Synthetic Growth Defect: 1

Sequence Information

ChrIV:1421150 to 1422478 | |

Genetic position: 306 cM

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1329	1421150..1422478	2008-06-05	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002891

KRE2 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for KRE2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for KRE2]

1)	Hausler A, et al. (1992) Yeast glycoprotein biosynthesis: MNT1 encodes an alpha-1,2-mannosyltransferase involved in O-glycosylation. Proc Natl Acad Sci U S A 89(15):6846-50
2)	Al-Aidroos K and Bussey H (1978) Chromosomal mutants of Saccharomyces cerevisiae affecting the cell wall binding site for killer factor. Can J Microbiol 24(3):228-37

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.