KRE2/YDR483W Summary Help

Standard Name KRE2 1
Systematic Name YDR483W
Alias MNT1 2
Feature Type ORF, Verified
Description Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication (2, 3)
Name Description Killer toxin REsistant 4
Chromosomal Location
ChrIV:1421157 to 1422485 | ORF Map | GBrowse
Gbrowse
Genetic position: 306 cM
Gene Ontology Annotations All KRE2 GO evidence and references
  View Computational GO annotations for KRE2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
unspecified
Resources
34 total interaction(s) for 26 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Co-purification: 3
  • PCA: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 9
  • Positive Genetic: 2
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 442
Molecular Weight (Da) 51,386
Isoelectric Point (pI) 5.17
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1421157 to 1422485 | ORF Map | GBrowse
SGD ORF map
Genetic position: 306 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1329 1421157..1422485 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002891
References cited on this page View Complete Literature Guide for KRE2
1) Hill K, et al.  (1992) Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Genetics 130(2):273-83
2) Hausler A, et al.  (1992) Yeast glycoprotein biosynthesis: MNT1 encodes an alpha-1,2-mannosyltransferase involved in O-glycosylation. Proc Natl Acad Sci U S A 89(15):6846-50
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Al-Aidroos K and Bussey H  (1978) Chromosomal mutants of Saccharomyces cerevisiae affecting the cell wall binding site for killer factor. Can J Microbiol 24(3):228-37