PRP3/YDR473C Summary

PRP3 BASIC INFORMATION

Standard Name	PRP3 1
Systematic Name	YDR473C
Alias	RNA3
Feature Type	ORF, Verified
Description	Splicing factor, component of the U4/U6-U5 snRNP complex (2)
Name Description	Pre-mRNA Processing 3

GO Annotations	All PRP3 GO evidence and references
	View Computational GO annotations for PRP3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	nuclear mRNA splicing, via spliceosome (IPI)
Cellular Component
Manually curated	U4/U6 x U5 tri-snRNP complex (IDA)

Mutant Phenotype	All PRP3 Phenotype details and references
Classical genetics
conditional	cold sensitivity: increased heat sensitivity: increased sporulation: absent
Large-scale survey
null	inviable

Interactions	PRP3 All interactions details and references
	107 total interaction(s) for 47 unique genes/features.
Physical Interactions	Affinity Capture-MS: 83 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Co-purification: 3 Reconstituted Complex: 1 Two-hybrid: 13
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Synthetic Rescue: 2

Sequence Information

ChrIV:1405847 to 1404438 | |

Note: this feature is encoded on the Crick strand.

Genetic position: 300 cM

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1410	1405847..1404438	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002881

PRP3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PRP3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRP3]

1)	Maddock, J. and Woolford, J. (1992) Personal Communication, Mortimer Map Edition 11
2)	Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31
3)	Vijayraghavan U, et al. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16

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